(Hyper)tension release by N-terminal acetylation.
نویسندگان
چکیده
A recent study links N-terminal acetylation and N-end rule degradation to blood pressure regulation. N-terminal mutants of Rgs2, a key G-protein regulator, are differentially processed by N-terminal acetyltransferases and the two branches of the N-end rule pathway. This leads to an imbalance in the signaling governing blood pressure.
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عنوان ژورنال:
- Trends in biochemical sciences
دوره 40 8 شماره
صفحات -
تاریخ انتشار 2015